Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | BIOCARTA_KERATINOCYTE DIFFERENTIATION |
| Enrichment Score (ES) | -0.64456475 |
| Normalized Enrichment Score (NES) | -1.7663382 |
| Nominal p-value | 0.0020661156 |
| FDR q-value | 0.11003004 |
| FWER p-Value | 0.38 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPK13 | 1448871_at | 1246 | 1.114 | -0.0264 | No | ||
| 2 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 1494 | 0.968 | -0.0112 | No | ||
| 3 | HRAS | 1422407_s_at 1424132_at | 2039 | 0.734 | -0.0159 | No | ||
| 4 | PPP2R5D | 1450560_a_at | 2764 | 0.533 | -0.0344 | No | ||
| 5 | RIPK1 | 1419508_at 1439273_at 1449485_at | 3565 | 0.402 | -0.0599 | No | ||
| 6 | CEBPA | 1418982_at | 3695 | 0.387 | -0.0552 | No | ||
| 7 | MAPK14 | 1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at | 4014 | 0.353 | -0.0601 | No | ||
| 8 | TRAF1 | 1423602_at 1445452_at | 5356 | 0.266 | -0.1141 | No | ||
| 9 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 6119 | 0.230 | -0.1426 | No | ||
| 10 | HOXA7 | 1449499_at | 6814 | 0.203 | -0.1688 | No | ||
| 11 | PLAT | 1415806_at 1458553_at | 10878 | 0.087 | -0.3520 | No | ||
| 12 | EGF | 1418093_a_at | 11661 | 0.066 | -0.3859 | No | ||
| 13 | TNF | 1419607_at | 11889 | 0.060 | -0.3946 | No | ||
| 14 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 12229 | 0.053 | -0.4087 | No | ||
| 15 | MAP2K3 | 1425456_a_at 1451714_a_at | 12727 | 0.040 | -0.4303 | No | ||
| 16 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 13273 | 0.025 | -0.4545 | No | ||
| 17 | JUN | 1417409_at 1448694_at | 13314 | 0.024 | -0.4557 | No | ||
| 18 | PRKCA | 1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at | 15821 | -0.071 | -0.5682 | No | ||
| 19 | SHC1 | 1422853_at 1422854_at | 16122 | -0.088 | -0.5795 | No | ||
| 20 | DAXX | 1419026_at | 16511 | -0.113 | -0.5941 | No | ||
| 21 | MAP2K1 | 1416351_at | 16691 | -0.127 | -0.5988 | No | ||
| 22 | FASLG | 1418803_a_at 1449235_at | 16829 | -0.139 | -0.6013 | No | ||
| 23 | RAF1 | 1416078_s_at 1425419_a_at | 16963 | -0.150 | -0.6033 | No | ||
| 24 | GRB2 | 1418508_a_at 1449111_a_at | 17171 | -0.170 | -0.6081 | No | ||
| 25 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 17377 | -0.194 | -0.6121 | No | ||
| 26 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 17435 | -0.202 | -0.6092 | No | ||
| 27 | PRKCE | 1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at | 17444 | -0.203 | -0.6040 | No | ||
| 28 | MAP2K6 | 1426850_a_at 1459292_at | 17524 | -0.215 | -0.6017 | No | ||
| 29 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 17646 | -0.231 | -0.6009 | No | ||
| 30 | SP1 | 1418180_at 1448994_at 1454852_at | 17912 | -0.267 | -0.6057 | No | ||
| 31 | MAPK3 | 1427060_at | 18642 | -0.385 | -0.6284 | No | ||
| 32 | SOS1 | 1421884_at 1421885_at 1421886_at | 18996 | -0.463 | -0.6319 | Yes | ||
| 33 | PRKCH | 1422079_at 1434248_at | 19272 | -0.527 | -0.6300 | Yes | ||
| 34 | IKBKB | 1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at | 19447 | -0.577 | -0.6221 | Yes | ||
| 35 | TRAF2 | 1451233_at | 19719 | -0.660 | -0.6164 | Yes | ||
| 36 | RELA | 1419536_a_at | 20015 | -0.767 | -0.6089 | Yes | ||
| 37 | FOS | 1423100_at | 20289 | -0.888 | -0.5970 | Yes | ||
| 38 | IKBKG | 1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at | 20443 | -0.967 | -0.5775 | Yes | ||
| 39 | BIRC2 | 1418854_at | 20613 | -1.064 | -0.5561 | Yes | ||
| 40 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 20696 | -1.127 | -0.5290 | Yes | ||
| 41 | PRKCQ | 1426044_a_at | 20851 | -1.253 | -0.5017 | Yes | ||
| 42 | FAS | 1460251_at | 20972 | -1.382 | -0.4693 | Yes | ||
| 43 | MAP3K1 | 1424850_at | 21128 | -1.590 | -0.4328 | Yes | ||
| 44 | TNFRSF1A | 1417291_at | 21181 | -1.673 | -0.3894 | Yes | ||
| 45 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 21477 | -2.135 | -0.3443 | Yes | ||
| 46 | ETS2 | 1416268_at 1437809_x_at 1447685_x_at | 21565 | -2.330 | -0.2845 | Yes | ||
| 47 | PRKCD | 1422847_a_at 1442256_at | 21582 | -2.392 | -0.2197 | Yes | ||
| 48 | MAP4K4 | 1422615_at 1440609_at 1448050_s_at 1459912_at | 21597 | -2.448 | -0.1533 | Yes | ||
| 49 | ETS1 | 1422027_a_at 1422028_a_at 1426725_s_at 1452163_at | 21603 | -2.483 | -0.0855 | Yes | ||
| 50 | BIRC3 | 1421392_a_at 1425223_at | 21850 | -3.673 | 0.0039 | Yes |
